Optic neuropathy

Optic neuropathy
Other namesOptic nerve disorder
SpecialtyNeurology, Ophthalmology
SymptomsVision loss, reduced color vision, blurred vision
ComplicationsPermanent vision loss, blindness
Usual onsetSudden or gradual
DurationVariable, depending on cause
TypesIschemic optic neuropathy, optic neuritis, traumatic optic neuropathy, hereditary optic neuropathy
CausesVascular issues, inflammation, trauma, toxins, genetic mutations (e.g., Leber's hereditary optic neuropathy)
Risk factorsAge, smoking, cardiovascular disease, genetic predisposition
Diagnostic methodClinical evaluation, visual field tests, optical coherence tomography, MRI
Differential diagnosisGlaucoma, retinal disease, brain lesions
PreventionManaging risk factors like blood pressure, avoiding smoking, regular eye exams
TreatmentAddressing underlying cause (e.g., steroids for inflammation,[1] surgery for trauma), vision rehabilitation
MedicationCorticosteroids (for optic neuritis), other medications depending on the cause
PrognosisVariable; some cases recover, others lead to permanent vision loss
FrequencyCommon in individuals with risk factors (e.g., older adults, smokers)
DeathsNone directly from optic neuropathy, but complications from underlying causes (e.g., stroke) can be fatal

Optic neuropathy is damage to the optic nerve from any cause. The optic nerve is a bundle of millions of fibers in the retina that sends visual signals to the brain.

Damage and death of these nerve cells, or neurons, leads to characteristic features of optic neuropathy. The main symptom is loss of vision, with colors appearing subtly washed out in the affected eye. A pale disc is characteristic of long-standing optic neuropathy. In many cases, only one eye is affected and a person may not be aware of the loss of color vision until the examiner asks them to cover the healthy eye.

Optic neuropathy is often called optic atrophy, to describe the loss of some or most of the fibers of the optic nerve.

  1. ^ Stunkel L, Van Stavern GP (2018). "Steroid Treatment of Optic Neuropathies". Asia-Pacific Journal of Ophthalmology. 7 (4). Philadelphia, Pa.: 218–228. doi:10.22608/APO.2018127. PMID 29962119.

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